Laboratory of Resilience Biology
Department of Developmental Biology, Stanford University School of Medicine
We study the fundamental principles of biological resilience: how living systems replace parts, compensate for damage, and adapt to stress to maintain function over time.
To understand these mechanisms, we develop and apply technologies that bridge engineering, computation, and biology to map and control physiological function across multiple scales within living animals.
Ultimately, we aim to create new ways of treating aging and disease by enhancing endogenous resilience processes to slow decline or restore lost function.
Mechanisms of Resilience
We study how biological systems maintain their function despite stress and damage.
By studying mechanisms of resilience at multiple scales, we aim to identify key pathways that protect cells and tissues throughout life, as well as how these fail with age.
Reading & Writing Biology
We develop new technologies to measure and manipulate biological systems at high resolution and a large scale.
By integrating neuroscience, imaging, functional genomics, and AI, we aim to map biological function in new ways within living animals, and to program new functionalities into cells in vivo.
Engineering Cells & Tissues
We translate fundamental insights into novel interventions to enhance or restore resilience.
Leveraging new technologies and discoveries, we aim to develop new ways of treating aging and disease that build upon the body's intrinsic capacity for adaptation and repair.